Assistant Professor
Department of Biological Sciences
Towson University
Towson, MD 21252 USA
Office: Smith 215A
Phone: 410-704-3124
Fax: 410-704-2405
email: csinclair@towson.edu
Education:
Postdoc Johns Hopkins University
Ph.D. Mayo Clinic and Foundation
M.S. Oklahoma State University
B.S. University of Dayton
Courses Taught:
Biol 213/214 - Anatomy & Physiology I and II
Biol 463/563 - Developmental Biology (Spring 2011)
Biol 601 - Cancer Biology (Fall 2010)
Research Interests:
My laboratory is involved in the study of genetic diversity in populations of
invertebrates and vertebrates. Current projects an analysis of the genetic
structure of terrestrial snail, Ventridens ligera, populations in the
Potomac River basin, DNA barcoding of the terrestrial snail genus Stenotrema,
an analysis of the genetic structure of gopher tortoise (Gopherus
polyphemus) populations in Florida and an analysis of the genetic structure
of relocated and local box turtles (Terrapene
carolina) in Montgomery County, Maryland.
Publications:
Sinclair, C.S., Dawes, P.J., and Seigel, R.A. Genetic structuring of Gopher Tortoise (Gopherus polyphemus) populations on the Kennedy Space Center, Florida. Under review.
Sinclair, CS. Surfing snails: Population genetics of land snail, Ventridens ligera (Stylommatophora: Zonitidae), in the Potomac Gorge. In press.
Dawes, PJ, Sinclair, CS, and Seigel, RA. (2008) Use of traditional turtle marking to obtain DNA for population studies. Herpetological
Review. 39:190-191.
Sinclair CS and Gresens SE. (2008) Discrimination of Cricotopus sp. (Diptera: Chironomidae) with mitochondrial gene cytochrome
oxidase I sequence". Bulletin for Entomological Research. 98:555-563.
Sinclair CS, Richmond RH, and Ostrander GK. (2007) Characterization of the telomere regions in scleractinian coral, Acropora
surculosa. Genetica 129:227-233.
Sinclair CS, Richmond RH, Knobbe ET, Basslear C and Ostrander GK. Passive dosemeters for measurement of ultraviolet radiation
in marine environments. In: GK Ostrander (ed) Techniques in Aquatic Toxicology, Vol. 2, Lewis Publishers/CRC Press, Boca Raton, FL. January 2005.
Domart-Coulon IJ, Sinclair CS, Hill RT, Tambutté S, Puverel S, and Ostrander GK. A basidiomycete isolated from the skeleton of
Pocillopora damicornis (Scleractinia) selectively stimulates short-term survival of coral skeletogenic cells. Marine Biology 144:583-592,
2004.
Adem C, Soderberg CL, Hafner K, Reynolds C, Slezak JM, Sinclair CS, Sellers TA, Schaid DJ, Couch F, Hartmann LC, Jenkins RB.
ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers. Genes Chromosomes
Cancer 41:1-11, 2004.
Sinclair CS, Rowley M, Naderi A, and Couch FJ. The 17q23 amplicon and breast cancer. Breast Cancer Research and Treatment
78:313-322, 2003.
Sinclair CS, Adem C, Naderi A, Soderberg C, Wu G-J, Johnson M, Wadum L, Couch VL, Sellers TA, Schaid D, Slezak J,
Fredericksen S, Ingle JN, Hartmann L, Jenkins RB, and Couch FJ. TBX2 is preferentially amplified in BRCA1 and BRCA2 related
breast tumors. Cancer Research 62:3587-3591, 2002.
Wu G-J, Sinclair CS, Hinson, S, Ingle JN, Roche PC, and Couch FJ. Structural analysis of the 17q22-q23 amplicon identifies
several independent targets of amplification in breast cancer cell lines and tumors. Cancer Research 61:4951-4955, 2001.
Reiter JL, Threadgill DW, Eley GD, Strunk KE, Danielson AJ, Sinclair CS, Pearsall RS, Green PJ, Yee D, Lampland AL,
Balasubramaniam S, Crossley TO, Magnuson TR, and Maihle NJ. Comparative genomic sequence analysis and isolation of
human and mouse alternative EGFR transcripts encoding truncated receptor isoforms. Genomics 71:1-20, 2001.
Graduate Student Projects:
Undergraduate Student Projects:
Ms. Teriakie Joseph and Ms. Amanda Mardiney: A genetic population study of the Northern
Dusky Salamanders
Ms. Malinda Ross: A genetic population study of relocated box turtles
Past Students:
Graduate:
Ms. Gina Meletakos
Mr. Pat Dawes
Undergraduate:
Mr. Oluwarotimi Folorunso,
Mr. Tony Basel
Ms. Rebecca McConnell
Mr. Evan Cameron
Mr. Daniel Cassilly
Mr. Wei (Jack) Guo
Mr. Grant Thomas
Ms. Sovath Chum
Ms. Deandra Prabhu
Ms. Sonia Thangavelu
Ms. Chelsea Scott