Senior Lecturer
Department of Biological Sciences
Towson University
Towson, MD 21252 USA
Office: Smith 353
Phone: 410-704-4816
Fax: 410-704-2405
email: lwilliamshogarth@towson.edu
Education:
Ph.D. Howard University
B.S. Georgetown University
Courses Taught:
BIOL 213/214 - Human Anatomy and Physiology I and II
BIOL 425 - Dissection of the Human Upper Extremity
BIOL 427 - Neuromuscular Mechanisms of the Upper Extremity
BIOL 604 - Mechanisms of Animal Physiology
Research Interests:
My research is focused on the investigation of mechanisms involved in nervous system development, degeneration and regeneration. We use the rodent olfactory system as our paradigm. Our approach takes advantage of the fact that the primary olfactory pathway naturally degenerates and regenerates throughout the lifespan of the organism. In my lab, we look at the embryonic, the normal adult, and the surgically manipulated-adult olfactory tissues. The concentration of our laboratory explorations is primarily on the cues that guide developing and regenerating olfactory receptor neurons to their target structure, the olfactory bulb.
Students in my lab employ the following techniques in their research:
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Recombinant DNA methods
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In situ hybridization
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Immunohistochemistry
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Cell culture
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Animal surgical manipulations
Publications:
L.C. Williams-Hogarth, A.C. Puche, C. Torrey, X. Cai, I. Song, A.L. Kolodkin, M.T. Shipley, and G.V. Ronnett. Expression of Semaphorins in
Developing and Regenerating Olfactory Epithelium. J Comp Neurol, 2000 (423) pp.565-578.
Graduate Students:
David Marks – Influence of Thyroid Hormone Deprivation on Olfactory Neuronal Differentiation